Traditional Systemics

Systemic medications are available by prescription only. Taken by mouth or by injection, they affect the entire body. Systemic drugs for psoriasis are typically prescribed when topical treatment fails to adequately treat psoriasis. These medications work by suppressing the overactive immune system in psoriatic disease. While typically more effective than topical medications, traditional systemic drugs can have a greater risk of side effects.

List of Traditional Systemic Drugs

How Does It Work?

Methotrexate can be used to treat psoriasis and the symptoms of psoriatic arthritis. Although the exact mechanism of methotrexate is not known, it is thought to work by regulating the overactive immune system that is present in patients with psoriasis and psoriatic arthritis.

How Is It Used?

Methotrexate is usually prescribed to be taken once per week. It is available as both a pill and an injection.

What are the possible side effects?

Common side effects of methotrexate treatment include diarrhea, nausea, vomiting, loss of appetite, inflammation of the lips and/or mouth, fatigue, and liver function abnormalities.

Rare side effects of methotrexate include serious reactions such as bone marrow suppression which includes low red blood cell counts or white blood cell counts, as well as decreased platelet counts.  Rarely, it could also potentially cause liver damage, lung damage, or immunosuppression. It can be teratogenic if taken while pregnant (i.e., cause malformations in the unborn child).  To obtain a comprehensive list of all known potential side effects of methotrexate, talk your doctor or pharmacist.

Any Other Important Considerations?

Methotrexate is not safe to take during pregnancy. If you become pregnant while taking methotrexate, contact your doctor immediately.

If you are on this medication, you should not be breastfeeding. If you are pregnant, may be pregnant, planning on becoming pregnant, breastfeeding, or planning to breast feed, speak with your prescriber before starting this medication.

While on this medication or if you just came off of this medication, if applicable, you should be on at least two forms of reliable birth control to prevent pregnancy as the drug can cause harm to an unborn baby. Make sure to discuss this with your prescriber.

Alcohol consumption is not recommended while taking methotrexate due to the risk of liver toxicity.

Since methotrexate is associated with rare, serious side effects, close monitoring by your doctor is recommended.

What Medications Interact With This Treatment?

Some medications that may interact with methotrexate include acitretin, cyclosporine, furosemide, NSAIDs (e.g., ibuprofen, naproxen), and trimethoprim/sulfamethoxazole. For a complete list of medications that may interact with methotrexate and to understand how a potential drug interaction should be managed, talk to your doctor or pharmacist.

Product Monograph

https://pdf.hres.ca/dpd_pm/00042486.PDF

The product monograph is created by Health Canada to summarize the evidence that it reviewed in order to permit this drug to be sold to patients in Canada. It includes information about the drug’s indication (reason for using it), side effects, and any safety warning information. This is used by prescribers, pharmacists, insurance providers and others to use the drug safely. The information can be very detailed and we encourage you to ask your healthcare provider any questions you may have.

This site is updated regularly; however this information is subject to change. For the most up-to-date information regarding product monographs, search here.

How Does It Work?

Cyclosporine is an oral medication often used in patients with liver, lung, or heart transplants. It works to treat psoriasis by regulating the immune system.

How Is It Used?

Cyclosporine is an oral medication dosed based on weight. The typical starting dose of cyclosporine is 2.5 mg/kg/day in two divided doses. The maximum dose of cyclosporine is 4 mg/kg/day.

What are the possible side effects?

It should be noted that because of the risk of toxicity, cyclosporine therapy should be limited to one year.  Common side effects of cyclosporine include abdominal pain, diarrhea, nausea, headache, increased blood pressure, and tremor. Due to the risk of rarer, more serious side effects such as potential liver or kidney damage, it is important to be monitored regularly by your doctor when taking cyclosporine. To obtain a comprehensive list of all known potential side effects of cyclosporine, talk your doctor or pharmacist.

Any Other Important Considerations?

Grapefruit juice can increase the amount of cyclosporine in the blood. Grapefruit juice should be avoided if you are taking cyclosporine.

What Medications Interact With This Treatment?

Some medications that may interact with cyclosporine include amiodarone, atorvastatin, carbamazepine, carvedilol, cochicine, dabigatran, echinacea, edoxaban, eplerenone, fluvastatin, lovastatin, methotrexate, mifepristone, NSAIDs (e.g., ibuprofen, naproxen), orlistat, pravastatin, repaglinide, ritonavir, rosuvastatin, simvastatin, and St. John’s wort.

For a complete list of medications that may interact with cyclosporine and to understand how a potential drug interaction should be managed, talk to your doctor or pharmacist. Before starting any new medications, ask a doctor or pharmacist if it is ok to take with cyclosporine.

Product Monograph

https://pdf.hres.ca/dpd_pm/00069722.PDF

The product monograph is created by Health Canada to summarize the evidence that it reviewed in order to permit this drug to be sold to patients in Canada. It includes information about the drug’s indication (reason for using it), side effects, and any safety warning information. This is used by prescribers, pharmacists, insurance providers and others to use the drug safely. The information can be very detailed and we encourage you to ask your healthcare provider any questions you may have.

This site is updated regularly; however this information is subject to change. For the most up-to-date information regarding product monographs, search here.

How Does It Work?

The exact mechanism of acitretin is unknown. It is thought to play a role in the multiplication of skin cells, and it may also have some immune-modulatory properties (i.e., regulates the immune system).

How Is It Used?

Acitretin is an oral medication and is typically taken with food in doses ranging from 25 to 50 mg per day.

What are the possible side effects?

Acitretin is teratogenic and should not be used in women of childbearing potential unless they plan to refrain from pregnancy for at least three years after discontinuing the drug. Common side effects of acitretin include hair loss, dry lips, dry skin, dry eyes, dry mouth, itchiness, joint pain, abnormal sensations such as tingling, and nose bleeds. Acitretin can also cause pancreatitis. If you notice depressive symptoms, have suicidal thoughts, or are experiencing nausea, vomiting, and headache while taking acitretin, it is important to consult your doctor. To obtain a comprehensive list of all known potential side effects of acitretin, talk your doctor or pharmacist.

Any Other Important Considerations?

Full improvement may not be seen for a few months, and temporary worsening of psoriasis may be seen initially.

Acitretin is a teratogen and increases the risk of significant birth defects. When treated with acitretin, two forms of reliable contraception to avoid pregnancy should be used starting one month prior to acitretin therapy through three years post-therapy.

Female patients of childbearing age are advised not to drink alcohol during acitretin therapy and for at least two months post-treatment, as alcohol can prolong the duration that acitretin has the ability to cause birth defects.

In general, treatment with acitretin should be discontinued when psoriasis sufficiently clears. Relapses of psoriasis may require acitretin to be restarted.

What Medications Interact With This Treatment?

Tetracycline antibiotics should not be taken while on acitretin therapy.

For a complete list of medications that may interact with acitretin and to understand how a potential drug interaction should be managed, talk to your doctor or pharmacist. Before starting any new medications, ask a doctor or pharmacist if it is ok to take with acitretin.

Product Monograph

https://pdf.hres.ca/dpd_pm/00046848.PDF

The product monograph is created by Health Canada to summarize the evidence that it reviewed in order to permit this drug to be sold to patients in Canada. It includes information about the drug’s indication (reason for using it), side effects, and any safety warning information. This is used by prescribers, pharmacists, insurance providers and others to use the drug safely. The information can be very detailed and we encourage you to ask your healthcare provider any questions you may have.

This site is updated regularly; however this information is subject to change. For the most up-to-date information regarding product monographs, search here.

How Does It Work?

Apremilast is a drug that regulates the immune system by decreasing inflammatory molecules that are associated with psoriasis and psoriatic arthritis.

How Is It Used?

Apremilast is an oral medication that is usually prescribed to be taken twice daily. When starting apremilast, your doctor may recommend starting at a lower dose and then increasing the dose each day until the recommended dose is reached. This is done to reduce the chance of side effects. Initial improvement of psoriasis may be noted as soon as the first few weeks of treatment.

What are the possible side effects?

Common side effects of apremilast include diarrhea, nausea, headache, and upper respiratory tract infections. It is important to contact your physician if you experience new or worsening depression, suicidal ideation, or other mood changes while on apremilast. To obtain a comprehensive list of all known potential side effects of apremilast, talk your doctor or pharmacist.

Any Other Important Considerations?

N/A

What Medications Interact With This Treatment?

Some medications can cause apremilast to be removed from the body faster, potentially reducing its effectiveness. Your physician or pharmacist can help you determine if you are on a medication that can reduce the effectiveness of apremilast.

St. John’s Wort, an over-the-counter natural health product, can reduce the effectiveness of apremilast. Use of St. John’s Wort is not recommended in patients taking apremilast.

Product Monograph

https://pdf.hres.ca/dpd_pm/00057499.PDF

The product monograph is created by Health Canada to summarize the evidence that it reviewed in order to permit this drug to be sold to patients in Canada. It includes information about the drug’s indication (reason for using it), side effects, and any safety warning information. This is used by prescribers, pharmacists, insurance providers and others to use the drug safely. The information can be very detailed and we encourage you to ask your healthcare provider any questions you may have.

This site is updated regularly; however this information is subject to change. For the most up-to-date information regarding product monographs, search here.

Patient Support Program

Call 1-844-ez-Start (1-844-397-8278) for information.

How Does It Work?

This medication was originally developed to treat inflammatory bowel diseases. Sulfasalazine is sometimes used to treat psoriatic arthritis. About 1/3 of psoriatic arthritis patients respond to sulfasalazine within 8-12 weeks. It works by suppressing the overactive immune system in psoriatic arthritis. This medication may also have anti-inflammatory effects.

How Is It Used?

It comes in regular tablet or long-acting tablets. Sulfasalazine should be taken after meals. Long-acting tablets should be swallowed whole without chewing, breaking, or crushing.What are the possible side effects?

Potential side effects of leflunomide include headache, hair loss, skin rash, diarrhea, nausea, abdominal pain, dizziness, and high blood pressure. To obtain a comprehensive list of all known potential side effects of leflunomide, talk your doctor or pharmacist.

What Are The Possible Side Effects?

Potential side effects of sulfasalazine include headache, skin rash, nausea, abdominal pain, vomiting, and weight loss. To obtain a comprehensive list of all known potential side effects of sulfasalazine, talk your doctor or pharmacist.

Any Other Important Considerations?

This is a sulfa drug. If you are allergic to sulfa, you may also be allergic to this medication.

It is important that you have your bloodwork and urine checked as directed by your doctor. This drug can also affect the results of certain tests, and you should notify healthcare providers that you take this medication.

This drug can cause certain problems with sperm in males and affect the patient’s ability to father a biological child. This usually resolves once the drug is stopped. Speak with your doctor.

If you are pregnant, planning on getting pregnant, breastfeeding, or planning on breastfeeding, speak with your doctor regarding the benefits and risks of taking this medication.

If you have kidney or liver disease, this drug may accumulate in your body and the risk of toxic effects may be increased. Please let your physician, nurse practitioner, or pharmacist know so that the dose can be adjusted accordingly or other options can be explored if necessary.

What Medications Interact With This Treatment?

Some examples of medications which interact with sulfasalazine include antibiotics, Warfarin or other blood thinners (i.e., rivaroxaban aka Xarelto), antidiabetic medications, Digoxin, Phenytoin. For a complete list of medications that may interact with sulfasalazine and to understand how a potential drug interaction should be managed, talk to your doctor or pharmacist. Before starting any new medications, ask a doctor or pharmacist if it is ok to take with sulfasalazine.

Product Monograph

 

https://pdf.hres.ca/dpd_pm/00049093.PDF

The product monograph is created by Health Canada to summarize the evidence that it reviewed in order to permit this drug to be sold to patients in Canada. It includes information about the drug’s indication (reason for using it), side effects, and any safety warning information. This is used by prescribers, pharmacists, insurance providers and others to use the drug safely. The information can be very detailed and we encourage you to ask your healthcare provider any questions you may have.

This site is updated regularly; however this information is subject to change. For the most up-to-date information regarding product monographs, search here.

How Does It Work?

NSAID stands for non-steroidal anti-inflammatory drugs.

Examples of NSAIDs include acetylsalicylic acid (Aspirin), ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), meloxicam, and diclofenac (Voltaren, Arthrotec).

NSAIDs are medicines that relieve pain and reduce inflammation by stopping a chemical process in the body that leads to inflammation. NSAIDs are also used to treat fever.

How Is It Used?

NSAIDs come in a variety of forms including oral forms, suppositories, topical, and injectable forms.

Some oral NSAIDs are available over-the-counter, whereas others are available by prescription only. Some of the over-the-counter NSAIDs are available by prescription only at certain strengths.

Pill forms should be taken with food to lessen stomach upset.

What Are The Possible Side Effects?

The most common potential side effects from NSAIDs are related to the stomach. Side effects may range from discomfort, to more rarely gastrointestinal bleeding, perforation, or ulceration. Less frequently, NSAIDs can have side effects related to the heart, kidneys, and skin. To obtain a comprehensive list of all known potential side effects of a specific NSAID, talk your doctor or pharmacist.

Any Other Important Considerations?

You should discuss whether or not it is safe for you to take NSAIDs with your doctor, primary care provider, or pharmacist if you have:

  • An ulcer in your stomach or intestine or if you have ever had bleeding from the gut
  • Heart disease (i.e., heart failure) or history of a stroke
  • Asthma or other lung conditions
  • Kidney disease
  • Liver disease
  • High blood pressure
  • Disorders that increase the risk of bleeding
  • Plans for a surgery

If you are pregnant, NSAIDs should be avoided during the last 3 months of pregnancy. Check with your healthcare provider if you are breastfeeding or planning to breastfeed.

Make sure to check with your physician, nurse practitioner, or a pharmacist regarding the maximum daily dose of an NSAID.

Acetaminophen (aka Tylenol) is not an NSAID, but it can be added on for pain relief. However, it does not have any effect on inflammation.

What Medications Interact With This Treatment?

Some examples of medications which interact with NSAIDs include diuretics (i.e., furosemide aka Lasix), blood pressure medications (i.e., beta blockers, hydrochlorothiazide), warfarin and other blood thinners (i.e., rivaroxaban aka Xarelto), lithium, cyclosporine, and certain antibiotics like trimethoprim-sulfamethoxazole (e.g., Septra). For a complete list of medications that may interact with specific NSAIDs and to understand how a potential drug interaction should be managed, talk to your doctor or pharmacist. Before starting any new medications, ask a doctor or pharmacist if it is ok to take with NSAIDs.

Public Drug Program Formulary Tables

There are many different NSAIDs, some of which are over-the-counter, and coverage may vary based on the specific drug.

Product Monograph

 

Acetysalicylic acid: https://pdf.hres.ca/dpd_pm/00037371.PDF
Ibuprofen: https://pdf.hres.ca/dpd_pm/00048560.PDF
Naproxen: https://pdf.hres.ca/dpd_pm/00039826.PDF
Meloxicam: https://pdf.hres.ca/dpd_pm/00041101.PDF
Diclofenac: https://pdf.hres.ca/dpd_pm/00043059.PDF

The product monograph is created by Health Canada to summarize the evidence that it reviewed in order to permit this drug to be sold to patients in Canada. It includes information about the drug’s indication (reason for using it), side effects, and any safety warning information. This is used by prescribers, pharmacists, insurance providers and others to use the drug safely. The information can be very detailed and we encourage you to ask your healthcare provider any questions you may have.

This site is updated regularly; however this information is subject to change. For the most up-to-date information regarding product monographs, search here.

How Does It Work?

Celecoxib is a type of NSAID (nonsteroidal anti-inflammatory drug) that has been shown to be less hard on the stomach compared to other NSAIDs according to some studies. It is used to relieve pain and reduce inflammation by stopping a chemical process in the body that leads to inflammation.

How Is It Used?

Celecoxib comes in capsule form that can be taken orally. It is recommended to take celecoxib with food.

What Are The Possible Side Effects?

The most common potential side effects from celecoxib are related to the stomach. Celecoxib is thought to have less gastrointestinal side effects than other NSAIDs. Side effects may range from discomfort, to more rarely gastrointestinal bleeding, perforation, or ulceration. Less frequently, celecoxib can have side effects related to the heart, kidneys, and skin. To obtain a comprehensive list of all known potential side effects of celecoxib, talk your doctor or pharmacist.

Any Other Important Considerations?

Celecoxib is not necessarily superior to regular NSAIDs in terms of effectiveness. It can be more costly than regular NSAIDs. It also has similar risks as NSAIDs with regards to risk of kidney disease or heart disease. Speak with your doctor about the benefits and risks of taking celecoxib.

Celecoxib should not be used in patients who are allergic to sulfa drugs as it has a similar chemical structure to sulfa drugs.

What Medications Interact With This Treatment?

Some examples of medications which interact with celecoxib include diuretics (i.e., furosemide aka Lasix), blood pressure medications (i.e., beta blockers, hydrochlorothiazide), warfarin and other blood thinners (i.e., rivaroxaban aka Xarelto), lithium, cyclosporine, and certain antibiotics like trimethoprim-sulfamethoxazole (e.g., Septra). For a complete list of medications that may interact with specific celecoxib and to understand how a potential drug interaction should be managed, talk to your doctor or pharmacist. Before starting any new medications, ask a doctor or pharmacist if it is ok to take with celecoxib.

Product Monograph

https://pdf.hres.ca/dpd_pm/00041466.PDF

The product monograph is created by Health Canada to summarize the evidence that it reviewed in order to permit this drug to be sold to patients in Canada. It includes information about the drug’s indication (reason for using it), side effects, and any safety warning information. This is used by prescribers, pharmacists, insurance providers and others to use the drug safely. The information can be very detailed and we encourage you to ask your healthcare provider any questions you may have.

This site is updated regularly; however this information is subject to change. For the most up-to-date information regarding product monographs, search here.

How Does It Work?

Tofacitinib is a medication that targets the overactive immune system in psoriatic arthritis. Tofacitinib works by inhibiting janus kinase enzymes, which are involved in immune system activity.

How Is It Used?

Tofacitinib is a medication taken by mouth. It is available as a 5 mg tablet taken twice a day or as an 11 mg tablet taken once a day.

What Are The Possible Side Effects?

The most common side effects of tofacitinib include bronchitis, diarrhea, dyspepsia, headache, nasopharyngitis, and nausea. To obtain a comprehensive list of all known potential side effects of tofacitinib, talk your doctor or pharmacist.

Any Other Important Considerations?

Use of tofacitinib is not recommended in patients with severe liver problems. Dosage reduction may be required in patients with liver or kidney impairment. Tofacitinib is also contraindicated in people who are pregnant and breastfeeding.

Lymphoma and other malignancies, serious infections and thrombosis have been reported in patients taking tofacitinib. Discuss with your health care provider what this may mean for you and the relative risk versus the potential benefits of tofacitinib.

An increased risk of adverse effects with tofacitinib has been noted when used in patients over the age of 65 and in Asian patients.

Some vaccinations, known as live vaccinations, should be avoided while on tofacitinib. Before receiving a vaccination, ask your healthcare provider if the vaccine is ok to receive while on tofacitinib.

What Medications Interact With This Treatment?

Some medications that may interact with tofacitinib include antiarrythmics beta-blockers, calcium channel blockers, cholinesterase inhibitors, HIRV protease inhibitors, rifampin, ketoclonozole, and fluconazole. It is not recommended to take tofacitinib with drugs such as azathioprine, cyclosporine, biologics or baricitini.

For a complete list of medications that may interact with tofacitinib and to understand how a potential drug interaction should be managed, talk to your doctor or pharmacist.

Product Monograph

https://pdf.hres.ca/dpd_pm/00075206.PDF

The product monograph is created by Health Canada to summarize the evidence that it reviewed in order to permit this drug to be sold to patients in Canada. It includes information about the drug’s indication (reason for using it), side effects, and any safety warning information. This is used by prescribers, pharmacists, insurance providers and others to use the drug safely. The information can be very detailed and we encourage you to ask your healthcare provider any questions you may have.

This site is updated regularly; however this information is subject to change. For the most up-to-date information regarding product monographs, search here.

Patient Support Program

https://www.pfizer.ca/assistance-programs

How Does It Work?

Rinvoq acts on specific molecular signals used by the immune system to decrease the immune system’s overactivity that can contribute to psoriatic arthritis. It works by inhibiting Janus kinase enzymes, which are involved in immune system activit

How Is It Used?

Rinvoq is an oral medication, typically coming in 15 mg tablets that are taken once a day.

What Are The Possible Side Effects?

The most common side effects of Rinvoq include increased risk of certain infections such as shingles, nausea, cough, liver irritation, and back pain. Rarer but serious side effects include severe infection such as pneumonia or cellulitis, osteoarthritis, blood clots, severe gastrointestinal tract damage, and increased risk of cancer development. Due to the potential or serious side effects, it is important to be monitored by a doctor when on Rinvoq. To obtain a comprehensive list of all potential side effects, talk to your doctor or pharmacist.

Any Other Important Considerations?

Rinvoq should be stopped while you have a serious infection.

What Medications Interact With This Treatment?

Drugs that have the potential to interact with Rinvoq include anti-fungals such as ketoconazole or antibiotics such as rifampin. Ask your doctor or pharmacist if you are concerned about a drug interaction, and always obtain approval from a doctor or pharmacist before starting Rinvoq.

Product Monograph

https://pdf.hres.ca/dpd_pm/00073108.PDF

The product monograph is created by Health Canada to summarize the evidence that it reviewed in order to permit this drug to be sold to patients in Canada. It includes information about the drug’s indication (reason for using it), side effects, and any safety warning information. This is used by prescribers, pharmacists, insurance providers and others to use the drug safely. The information can be very detailed and we encourage you to ask your healthcare provider any questions you may have.

This site is updated regularly; however this information is subject to change. For the most up-to-date information regarding product monographs, search here.

Patient Support Program

https://rinvoq.abbviecare.ca/en

Public Drug Program Formulary Tables

ProvinceClassGeneric NameDrug NamePsoriasisPsoriatic Arthritis
AlbertaBiologics and BiosimilarsAbataceptOrencia®NoNo
AlbertaSystemic DrugsAcitretinSoriatane®YesN/A
AlbertaBiologics and BiosimilarsAdalimumabHumira®NoNo
AlbertaBiologics and BiosimilarsAdalimumabHadlima®Yes - S/AYes - S/A
AlbertaBiologics and BiosimilarsAdalimumabHyrimoz®Yes - S/AYes - S/A
AlbertaBiologics and BiosimilarsAdalimumabIdacio®Yes - S/AYes - S/A
AlbertaBiologics and BiosimilarsAdalimumabAmgevita®Yes - S/AYes - S/A
AlbertaBiologics and BiosimilarsAdalimumabHulio®Yes - S/AYes - S/A
AlbertaBiologics and BiosimilarsAdalimumabAbriladaYes – S/AYes – S/A
AlbertaBiologics and BiosimilarsAdalimumabSimlandiYes – S/AYes – S/A
AlbertaBiologics and BiosimilarsAdalimumabYuflymaYes – S/AYes – S/A
AlbertaSystemic DrugsApremilastOtezla®NoNo
AlbertaBiologics and BiosimilarsBimekizumabBimzelxYes – S/ANo
AlbertaBiologics and BiosimilarsBrodalumabSiliq™NoN/A
AlbertaSystemic DrugsCelecoxibCelebrexNoNo
AlbertaBiologics and BiosimilarsCertolizumab pegolCimzia®NoYes – S/A
AlbertaPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_GelYesN/A
AlbertaPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_OintmentYesN/A
AlbertaPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsEnstilar™_FoamYesN/A
AlbertaSystemic DrugsCyclosporineYes – S/AN/A
AlbertaBiologics and BiosimilarsEtanerceptEnbrel®NoNo
AlbertaBiologics and BiosimilarsEtanerceptErelzi™Yes – S/A Yes – S/A
AlbertaBiologics and BiosimilarsEtanerceptBrenzys®Yes – S/AYes – S/A
AlbertaBiologics and BiosimilarsEtanerceptRymtiYes - S/AYes - S/A
AlbertaBiologics and BiosimilarsGolimumabSimponi®N/AYes – S/A
AlbertaBiologics and BiosimilarsGuselkumabTremfya®Yes - S/AYes - S/A
AlbertaPrescription Topical TreatmentsHalobetasol propionate and tazaroteneDUOBRII®Yes - S/AN/A
AlbertaBiologics and BiosimilarsInfliximabRemicade®NoNo 
AlbertaBiologics and BiosimilarsInfliximabAvsola®Yes – S/AYes – S/A
AlbertaBiologics and BiosimilarsInfliximabInflectra®Yes – S/AYes – S/A
British ColumbiaBiologics and BiosimilarsAbataceptOrencia®NoNo
British ColumbiaSystemic DrugsAcitretinSoriatane®YesN/A
British ColumbiaBiologics and BiosimilarsAdalimumabHumira®No – S/A requests for psoriasis patients who are unable to transition to biosimilar could be considered on an exceptional case-by-case basis.  No – S/A requests for psoriatic arthritis patients who are unable to transition to biosimilar could be considered on an exceptional case-by-case basis.  
British ColumbiaBiologics and BiosimilarsAdalimumabHadlima®Yes - S/AYes - S/A
British ColumbiaBiologics and BiosimilarsAdalimumabHyrimoz®Yes - S/AYes - S/A
British ColumbiaBiologics and BiosimilarsAdalimumabIdacio®Yes - S/AYes - S/A
British ColumbiaBiologics and BiosimilarsAdalimumabAmgevita®Yes - S/AYes - S/A
British ColumbiaBiologics and BiosimilarsAdalimumabHulio®Yes - S/AYes - S/A
British ColumbiaBiologics and BiosimilarsAdalimumabAbriladaYes - S/AYes - S/A
British ColumbiaBiologics and BiosimilarsAdalimumabSimlandiYes - S/AYes - S/A
British ColumbiaBiologics and BiosimilarsAdalimumabYuflymaYes - S/AYes - S/A
British ColumbiaSystemic DrugsApremilastOtezla®NoNo
British ColumbiaBiologics and BiosimilarsBimekizumabBimzelxYes - S/ANo
British ColumbiaBiologics and BiosimilarsBrodalumabSiliq™NoN/A
British ColumbiaSystemic DrugsCelecoxibCelebrexNoYes – S/A
British ColumbiaBiologics and BiosimilarsCertolizumab pegolCimzia®NoYes - S/A
British ColumbiaPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_GelYesN/A
British ColumbiaPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_OintmentNoN/A
British ColumbiaPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsEnstilar™_FoamNoN/A
British ColumbiaSystemic DrugsCyclosporineYes – S/AN/A
British ColumbiaBiologics and BiosimilarsetanerceptEnbrel®No – S/A requests for psoriasis patients who are unable to transition to biosimilar could be considered on an exceptional case-by-case basis.  No – S/A requests for psoriatic arthritis patients who are unable to transition to biosimilar could be considered on an exceptional case-by-case basis.  
British ColumbiaBiologics and BiosimilarsEtanerceptErelzi™Yes - S/AYes – S/A
British ColumbiaBiologics and BiosimilarsEtanerceptBrenzys®Yes - S/AYes – S/A
British ColumbiaBiologics and BiosimilarsGolimumabSimponi®N/AYes – S/A
British ColumbiaBiologics and BiosimilarsGuselkumabTremfya®NoNo
British ColumbiaPrescription Topical TreatmentsHalobetasol propionate and tazaroteneDUOBRII®NoN/A
British ColumbiaBiologics and BiosimilarsInfliximabRemicade®NoNo 
British ColumbiaBiologics and BiosimilarsInfliximabAvsola®Yes – S/AYes – S/A
British ColumbiaBiologics and BiosimilarsInfliximabInflectra®Yes – S/AYes – S/A
ManitobaBiologics and BiosimilarsAbataceptOrencia®NoNo
ManitobaSystemic DrugsAcitretinSoriatane®, Mint-Acitretin, Taro-AcitretinYesN/A
ManitobaBiologics and BiosimilarsAdalimumabHumira®Yes - EDS. Hadlima, Hyrimoz, Idacio, Amgevita or Idacio will be the preferred adalimumab option for all adalimumab-naïve patients prescribed an adalimumab product for psoriasis.Yes - EDS. Hadlima, Hyrimoz, Idacio, Amgevita or Idacio will be the preferred adalimumab option for all adalimumab-naïve patients prescribed an adalimumab product for psoriatic arthritis.
ManitobaBiologics and BiosimilarsAdalimumabHadlima®Yes - EDSYes - EDS
ManitobaBiologics and BiosimilarsAdalimumabHyrimoz®Yes - EDSYes - EDS
ManitobaBiologics and BiosimilarsAdalimumabIdacio®Yes - EDSYes - EDS
ManitobaBiologics and BiosimilarsAdalimumabAmgevita®Yes - EDSYes - EDS
ManitobaBiologics and BiosimilarsAdalimumabHulio®Yes - EDSYes - EDS
ManitobaBiologics and BiosimilarsAdalimumabAbriladaYes - EDSYes - EDS
ManitobaBiologics and BiosimilarsAdalimumabSimlandiYes - EDSYes - EDS
ManitobaBiologics and BiosimilarsAdalimumabYuflymaYes - EDSYes - EDS
ManitobaSystemic DrugsApremilastOtezla®NoNo
ManitobaBiologics and BiosimilarsBimekizumabBimzelxYes - EDSNo
ManitobaSystemic DrugsCelecoxibCelebrex, CelecoxibYesYes
ManitobaBiologics and BiosimilarsCertolizumab pegolCimzia®NoYes – EDS
ManitobaPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_GelYesN/A
ManitobaPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_OintmentYesN/A
ManitobaPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsEnstilar™_FoamYesN/A
ManitobaSystemic DrugsCyclosporineRequires EDS, delete this row?YesN/A
ManitobaSystemic DrugsCyclosporineNeoral, Cyclosporine(Strides), Sandoz CyclosporineYes – EDSN/A
ManitobaBiologics and BiosimilarsEtanerceptEnbrel®Yes – EDS. Erelzi or Brenzys will be the preferred etanercept option for all etanercept-naïve patients prescribed an etanercept product for psoriasis.Yes – EDS. Erelzi or Brenzys will be the preferred etanercept option for all etanercept-naïve patients prescribed an etanercept product for psoriatic arthritis.
ManitobaBiologics and BiosimilarsEtanerceptErelzi™Yes – EDS  Yes – EDS
ManitobaBiologics and BiosimilarsEtanerceptBrenzys®Yes - EDSYes - EDS
ManitobaBiologics and BiosimilarsGolimumabSimponi®N/AYes – EDS
ManitobaBiologics and BiosimilarsGuselkumabTremfya®Yes - EDSYes - EDS
ManitobaPrescription Topical TreatmentsHalobetasol propionate and tazaroteneDUOBRII®YesN/A
ManitobaBiologics and BiosimilarsInfliximabRemicade®Yes – EDS. Inflectra, Renflexis or Avsola will be the preferred infliximab option for all infliximab-naïve patients prescribed an infliximab product.Yes – EDS. Inflectra, Renflexis or Avsola will be the preferred infliximab option for all infliximab-naïve patients prescribed an infliximab product.
ManitobaBiologics and BiosimilarsInfliximabAvsola®Yes - EDSYes - EDS
ManitobaBiologics and BiosimilarsInfliximabInflectra®Yes – EDSYes – EDS
New BrunswickBiologics and BiosimilarsAbataceptOrencia®NoNo
New BrunswickSystemic DrugsAcitretinSoriatane®YesN/A
New BrunswickBiologics and BiosimilarsAdalimumabHumira®NoNo
New BrunswickBiologics and BiosimilarsAdalimumabHadlima®Yes - S/AYes - S/A
New BrunswickBiologics and BiosimilarsAdalimumabHyrimoz®Yes - S/AYes - S/A
New BrunswickBiologics and BiosimilarsAdalimumabIdacio®Yes - S/AYes - S/A
New BrunswickBiologics and BiosimilarsAdalimumabAmgevita®Yes - S/AYes - S/A
New BrunswickBiologics and BiosimilarsAdalimumabHulio®Yes - S/AYes - S/A
New BrunswickBiologics and BiosimilarsAdalimumabAbriladaYes – S/AYes – S/A
New BrunswickBiologics and BiosimilarsAdalimumabSimlandiYes – S/AYes – S/A
New BrunswickBiologics and BiosimilarsAdalimumabYuflymaYes – S/AYes – S/A
New BrunswickSystemic DrugsApremilastOtezla®NoNo
New BrunswickBiologics and BiosimilarsBimekizumabBimzelxYes – S/ANo
New BrunswickBiologics and BiosimilarsBrodalumabSiliq™Yes – S/AN/A
New BrunswickSystemic DrugsCelecoxibCelebrexN/AYes
New BrunswickBiologics and BiosimilarsCertolizumab pegolCimzia®NoYes – S/A
New BrunswickPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_GelYesN/A
New BrunswickPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_OintmentYesN/A
New BrunswickPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsEnstilar™_FoamYesN/A
New BrunswickSystemic DrugsCyclosporineYesN/A
New BrunswickBiologics and BiosimilarsEtanerceptEnbrel®NoNo
New BrunswickBiologics and BiosimilarsEtanerceptErelzi™Yes – S/A Yes – S/A
New BrunswickBiologics and BiosimilarsEtanerceptBrenzys®Yes - S/AYes - S/A
New BrunswickBiologics and BiosimilarsEtanerceptRymtiYes – S/AYes – S/A
New BrunswickBiologics and BiosimilarsGolimumabSimponi®N/AYes – S/A
New BrunswickBiologics and BiosimilarsGuselkumabTremfya®Yes – S/AYes – S/A
New BrunswickPrescription Topical TreatmentsHalobetasol propionate and tazaroteneDUOBRII®YesN/A
New BrunswickBiologics and BiosimilarsInfliximabRemicade®NoNo
New BrunswickBiologics and BiosimilarsInfliximabAvsola®Yes - S/AYes - S/A
New BrunswickBiologics and BiosimilarsInfliximabInflectra®Yes - S/AYes - S/A
Newfoundland and LabradorBiologics and BiosimilarsAbataceptOrencia®NoNo
Newfoundland and LabradorSystemic DrugsAcitretinSoriatane®YesN/A
Newfoundland and LabradorBiologics and BiosimilarsAdalimumabHumira®Yes - S/A All SA requests for coverage of adalimumab for adalimumab- naïve patients will be assessed for the biosimilars of adalimumab only. Patients whose initial Special Authority was received before April 17, 2021 will be eligible for coverage of Humira.Yes - S/A All SA requests for coverage of adalimumab for adalimumab- naïve patients will be assessed for the biosimilars of adalimumab only. Patients whose initial Special Authority was received before April 17, 2021 will be eligible for coverage of Humira.
Newfoundland and LabradorBiologics and BiosimilarsAdalimumabHadlima®Yes - S/AYes - S/A
Newfoundland and LabradorBiologics and BiosimilarsAdalimumabHyrimoz®Yes - S/AYes - S/A
Newfoundland and LabradorBiologics and BiosimilarsAdalimumabIdacio®Yes - S/AYes - S/A
Newfoundland and LabradorBiologics and BiosimilarsAdalimumabAmgevita®Yes - S/AYes - S/A
Newfoundland and LabradorBiologics and BiosimilarsAdalimumabHulio®Yes - S/AYes - S/A
Newfoundland and LabradorBiologics and BiosimilarsAdalimumabAbriladaYes – S/AYes – S/A
Newfoundland and LabradorBiologics and BiosimilarsAdalimumabSimlandiYes – S/AYes – S/A
Newfoundland and LabradorBiologics and BiosimilarsAdalimumabYuflymaYes – S/AYes – S/A
Newfoundland and LabradorSystemic DrugsApremilastOtezla®NoNo
Newfoundland and LabradorBiologics and BiosimilarsBimekizumabBimzelxYes – S/ANo
Newfoundland and LabradorBiologics and BiosimilarsBrodalumabSiliq™Yes – S/AN/A
Newfoundland and LabradorSystemic DrugsCelecoxibN/AYes
Newfoundland and LabradorBiologics and BiosimilarsCertolizumab pegolCimzia®NoYes – S/A
Newfoundland and LabradorPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_GelYes – S/AN/A
Newfoundland and LabradorPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_OintmentNoN/A
Newfoundland and LabradorPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsEnstilar™_FoamYesN/A
Newfoundland and LabradorSystemic DrugsCyclosporineYesN/A
Newfoundland and LabradorBiologics and BiosimilarsEtanerceptEnbrel®NoNo
Newfoundland and LabradorBiologics and BiosimilarsEtanerceptErelzi™Yes – S/A Yes – S/A
Newfoundland and LabradorBiologics and BiosimilarsEtanerceptBrenzys®Yes – S/A Yes – S/A 
Newfoundland and LabradorBiologics and BiosimilarsGolimumabSimponi®N/AYes – S/A
Newfoundland and LabradorBiologics and BiosimilarsGuselkumabTremfya®Yes – S/A Yes – S/A 
Newfoundland and LabradorPrescription Topical TreatmentsHalobetasol propionate and tazaroteneDUOBRII®Yes – S/A N/A
Newfoundland and LabradorBiologics and BiosimilarsInfliximabRemicade®Yes – S/A; Inflectra or Renflexis are the preferred infliximab therapy for treatment naïve patients (coverage will only be considered for Remicade in patients stabilized prior to June 1, 2016). No
Newfoundland and LabradorBiologics and BiosimilarsInfliximabAvsola®Yes - S/AYes - SA
Newfoundland and LabradorBiologics and BiosimilarsInfliximabInflectra®Yes – S/AYes – S/A
NIHBBiologics and BiosimilarsAbataceptOrencia®NoNo
NIHBSystemic DrugsAcitretinSoriatane®YesN/A
NIHBBiologics and BiosimilarsAdalimumabHumira®Yes- only for clients who received approval for Humira before June 11, 2021Yes- only for clients who received approval for Humira before June 11, 2021
NIHBBiologics and BiosimilarsAdalimumabHadlima®Yes - L/UYes - L/U
NIHBBiologics and BiosimilarsAdalimumabHyrimoz®Yes - L/UYes - L/U
NIHBBiologics and BiosimilarsAdalimumabIdacio®Yes - L/UYes - L/U
NIHBBiologics and BiosimilarsAdalimumabAmgevita®Yes - L/UYes - L/U
NIHBBiologics and BiosimilarsAdalimumabHulio®Yes - L/UYes - L/U
NIHBBiologics and BiosimilarsAdalimumabAbriladaYes – L/UYes – S/A
NIHBBiologics and BiosimilarsAdalimumabSimlandiYes - L/UYes - L/U
NIHBBiologics and BiosimilarsAdalimumabYuflymaYes - L/UYes - L/U
NIHBSystemic DrugsApremilastOtezla®YesNo 
NIHBBiologics and BiosimilarsBimekizumabBimzelxNoNo
NIHBBiologics and BiosimilarsBrodalumabSiliq™Yes – L/UN/A
NIHBSystemic DrugsCelecoxibCelebrexN/AYes
NIHBBiologics and BiosimilarsCertolizumab pegolCimzia®NoYes – L/U
NIHBPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_GelYesN/A
NIHBPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_OintmentYesN/A
NIHBPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsEnstilar™_FoamYesN/A
NIHBSystemic DrugsCyclosporineCyclosporineYesYes
NIHBBiologics and BiosimilarsEtanerceptEnbrel®NoYes- Only for clients who received approval for Enbrel before October 2, 2017
NIHBBiologics and BiosimilarsEtanerceptErelzi™NoYes- L/U
NIHBBiologics and BiosimilarsEtanerceptBrenzys®NoYes - L/U
NIHBBiologics and BiosimilarsEtanerceptRymtiNoYes - L/U
NIHBBiologics and BiosimilarsGolimumabSimponi®N/AYes – L/U
NIHBBiologics and BiosimilarsGuselkumabTremfya®Yes - L/UYes - L/U
NIHBPrescription Topical TreatmentsHalobetasol propionate and tazaroteneDUOBRII®YesN/A
NIHBBiologics and BiosimilarsInfliximabRemicade®NoNo
NIHBBiologics and BiosimilarsInfliximabAvsola®Yes - L/UYes - L/U
NIHBBiologics and BiosimilarsInfliximabInflectra®Yes - L/UYes - L/U
Northwest TerritoriesBiologics and BiosimilarsAbataceptOrencia®NoNo
Northwest TerritoriesSystemic DrugsAcitretinSoriatane®YesN/A
Northwest TerritoriesBiologics and BiosimilarsAdalimumabHumira®Yes - L/UYes - L/U
Northwest TerritoriesBiologics and BiosimilarsAdalimumabHadlima®Yes - L/UYes - L/U
Northwest TerritoriesBiologics and BiosimilarsAdalimumabHyrimoz®Yes - L/UYes - L/U
Northwest TerritoriesBiologics and BiosimilarsAdalimumabIdacio®Yes - L/UYes - L/U
Northwest TerritoriesBiologics and BiosimilarsAdalimumabAmgevita®Yes - L/UYes - L/U
Northwest TerritoriesBiologics and BiosimilarsAdalimumabHulio®Yes - L/UYes - L/U
Northwest TerritoriesBiologics and BiosimilarsAdalimumabAbriladaYes - L/UYes - L/U
Northwest TerritoriesBiologics and BiosimilarsAdalimumabSimlandiYes - L/UYes - L/U
Northwest TerritoriesBiologics and BiosimilarsAdalimumabYuflymaYes - L/UYes - L/U
Northwest TerritoriesSystemic DrugsApremilastOtezla®Yes - L/UNo
Northwest TerritoriesBiologics and BiosimilarsBimekizumabBimzelxNoNo
Northwest TerritoriesBiologics and BiosimilarsBrodalumabSiliq™Yes – L/UN/A
Northwest TerritoriesSystemic DrugsCelecoxibCelebrexN/AYes
Northwest TerritoriesBiologics and BiosimilarsCertolizumab pegolCimzia®NoYes – L/U
Northwest TerritoriesPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_GelYesN/A
Northwest TerritoriesPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_OintmentYesN/A
Northwest TerritoriesPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsEnstilar™_FoamYesN/A
Northwest TerritoriesSystemic DrugsCyclosporineYesYes
Northwest TerritoriesBiologics and BiosimilarsEtanerceptEnbrel®NoYes – L/U
Northwest TerritoriesBiologics and BiosimilarsEtanerceptErelzi™Yes- L/UYes – L/U
Northwest TerritoriesBiologics and BiosimilarsEtanerceptBrenzys®NoYes - L/U
Northwest TerritoriesBiologics and BiosimilarsEtanerceptRymtiNoYes - L/U
Northwest TerritoriesBiologics and BiosimilarsGolimumabSimponi®N/AYes – L/U
Northwest TerritoriesBiologics and BiosimilarsGuselkumabTremfya®Yes - L/UYes - L/U
Northwest TerritoriesPrescription Topical TreatmentsHalobetasol propionate and tazaroteneDUOBRII®YesN/A
Northwest TerritoriesBiologics and BiosimilarsInfliximabRemicade®NoNo
Northwest TerritoriesBiologics and BiosimilarsInfliximabAvsola®Yes - L/UYes - L/U
Northwest TerritoriesBiologics and BiosimilarsInfliximabInflectra®Yes – L/UYes – L/U
Nova ScotiaBiologics and BiosimilarsAbataceptOrencia®NoNo
Nova ScotiaSystemic DrugsAcitretinSoriatane®YesN/A
Nova ScotiaBiologics and BiosimilarsAdalimumabHumira®Yes- only for clients who received approval for Humira before December 15, 2021Yes- only for clients who received approval for Humira before December 15, 2021
Nova ScotiaBiologics and BiosimilarsAdalimumabHadlima®Yes – EDSYes – EDS
Nova ScotiaBiologics and BiosimilarsAdalimumabHyrimoz®Yes – EDSYes – EDS
Nova ScotiaBiologics and BiosimilarsAdalimumabIdacio®Yes – EDSYes – EDS
Nova ScotiaBiologics and BiosimilarsAdalimumabAmgevita®Yes – EDSYes – EDS
Nova ScotiaBiologics and BiosimilarsAdalimumabHulio®Yes – EDSYes – EDS
Nova ScotiaBiologics and BiosimilarsAdalimumabAbriladaYes – EDSYes – EDS
Nova ScotiaBiologics and BiosimilarsAdalimumabSimlandiYes – EDSYes – EDS
Nova ScotiaBiologics and BiosimilarsAdalimumabYuflymaYes – EDSYes – EDS
Nova ScotiaSystemic DrugsApremilastOtezla®YesYes
Nova ScotiaBiologics and BiosimilarsBimekizumabBimzelxYes – EDSNo
Nova ScotiaBiologics and BiosimilarsBrodalumabSiliq™Yes – EDSN/A
Nova ScotiaSystemic DrugsCelecoxibCelebrexN/ANo
Nova ScotiaBiologics and BiosimilarsCertolizumab pegolCimzia®NoYes – EDS
Nova ScotiaPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_GelYes – EDSN/A
Nova ScotiaPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_OintmentNoN/A
Nova ScotiaPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsEnstilar™_FoamYes – EDSN/A
Nova ScotiaSystemic DrugsCyclosporineYesN/A
Nova ScotiaBiologics and BiosimilarsEtanerceptEnbrel®Yes – EDS; for etanercept-naïve patients whose etanercept therapy is initiated after Nov 1, 2017, a biosimilar will be the product that is approved.  Yes – EDS; for etanercept-naïve patients whose etanercept therapy is initiated after Nov 1, 2017, a biosimilar will be the product that is approved.  
Nova ScotiaBiologics and BiosimilarsEtanerceptErelzi™NoYes – EDS
Nova ScotiaBiologics and BiosimilarsEtanerceptBrenzys®Yes - EDSYes - EDS
Nova ScotiaBiologics and BiosimilarsEtanerceptRymtiYes - EDSYes - EDS
Nova ScotiaBiologics and BiosimilarsGolimumabSimponi®NoYes – EDS
Nova ScotiaBiologics and BiosimilarsGuselkumabTremfya®Yes – EDSYes – EDS
Nova ScotiaPrescription Topical TreatmentsHalobetasol propionate and tazaroteneDUOBRII®NoN/A
Nova ScotiaBiologics and BiosimilarsInfliximabRemicade®Yes – S/A. For infliximab naïve patients whose infliximab therapy is initiated after June 1, 2016, an infliximab biosimilar will be the product approved. Yes – S/A. For infliximab naïve patients whose infliximab therapy is initiated after June 1, 2016, an infliximab biosimilar will be the product approved. 
Nova ScotiaBiologics and BiosimilarsInfliximabAvsola®Yes – EDSYes – EDS
Nova ScotiaBiologics and BiosimilarsInfliximabInflectra®Yes – EDSYes – EDS
NunavutBiologics and BiosimilarsAdalimumabAbriladaYes - L/UYes - L/U
NunavutBiologics and BiosimilarsAdalimumabAmgevita®Yes - L/UYes - L/U
NunavutSystemic DrugsLeflunomideArava®N/AYes
NunavutBiologics and BiosimilarsInfliximabAvsola®Yes - L/UYes - L/U
NunavutBiologics and BiosimilarsBimekizumabBimzelxNoNo
NunavutBiologics and BiosimilarsEtanerceptBrenzys®NoYes - L/U
NunavutPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcipotriol - Dovonex®YesN/A
NunavutPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcitriol - Silkis®NoN/A
NunavutSystemic DrugsCelecoxibCelebrexN/AYes
NunavutBiologics and BiosimilarsCertolizumab pegolCimzia®NoYes – L/U
NunavutBiologics and BiosimilarsSecukinumabCosentyx®Yes – L/UYes – L/U
NunavutPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_GelYesN/A
NunavutPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_OintmentYesN/A
NunavutPrescription Topical TreatmentsHalobetasol propionate and tazaroteneDUOBRII®YesN/A
NunavutBiologics and BiosimilarsEtanerceptEnbrel®NoYes – L/U
NunavutPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsEnstilar™_FoamYesN/A
NunavutBiologics and BiosimilarsEtanerceptErelzi™Yes- L/UYes – L/U
NunavutBiologics and BiosimilarsAdalimumabHadlima®Yes - L/UYes - L/U
NunavutBiologics and BiosimilarsAdalimumabHulio®Yes - L/UYes - L/U
NunavutBiologics and BiosimilarsAdalimumabHumira®Yes - L/UYes - L/U
NunavutBiologics and BiosimilarsAdalimumabHyrimoz®Yes - L/UYes - L/U
NunavutBiologics and BiosimilarsAdalimumabIdacio®Yes - L/UYes - L/U
NunavutBiologics and BiosimilarsTildrakizumabIlumya™NoN/A
NunavutBiologics and BiosimilarsInfliximabInflectra®Yes – L/UYes – L/U
NunavutBiologics and BiosimilarsInfliximabOmvyence™NoNo
NunavutBiologics and BiosimilarsAbataceptOrencia®NoNo
NunavutSystemic DrugsApremilastOtezla®YesNo
NunavutBiologics and BiosimilarsInfliximabRemicade®NoNo
NunavutBiologics and BiosimilarsInfliximabRemsima™NoNo
NunavutBiologics and BiosimilarsInfliximabRenflexis®Yes - L/UYes - L/U
OntarioBiologics and BiosimilarsAbataceptOrencia®N/ANo. EAP may cover in specific clinical circumstances. 
OntarioSystemic DrugsAcitretinSoriatane®YesN/A
OntarioBiologics and BiosimilarsAdalimumabAbriladaYes - L/UYes - L/U
OntarioBiologics and BiosimilarsAdalimumabAmgevita®Yes - L/UYes - L/U
OntarioBiologics and BiosimilarsAdalimumabHadlima®Yes - L/UYes - L/U
OntarioBiologics and BiosimilarsAdalimumabHulio®Yes - L/UYes - L/U
OntarioBiologics and BiosimilarsAdalimumabHumira®Yes - EAPYes - EAP
OntarioBiologics and BiosimilarsAdalimumabHyrimoz®Yes - L/UYes - L/U
OntarioBiologics and BiosimilarsAdalimumabIdacio®Yes - L/UYes - L/U
OntarioBiologics and BiosimilarsAdalimumabSimlandiYes - L/UYes - L/U
OntarioBiologics and BiosimilarsAdalimumabYuflymaYes - L/UYes - L/U
OntarioSystemic DrugsApremilastOtezla®YesYes
OntarioBiologics and BiosimilarsBimekizumabBimzelxYes - L/UNo
OntarioBiologics and BiosimilarsBrodalumabSiliq™Yes – L/UN/A
OntarioSystemic DrugsCelecoxibCelebrexN/ANo
OntarioBiologics and BiosimilarsCertolizumab pegolCimzia®NoYes – EAP
OntarioPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_GelYes – in specific clinical situationsN/A
OntarioPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_OintmentYes – in specific clinical situationsN/A
OntarioPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsEnstilar™_FoamYes – in specific clinical situationsN/A
OntarioSystemic DrugsCyclosporineYesN/A
OntarioBiologics and BiosimilarsEtanerceptBrenzys®Yes – L/U Yes – L/U
OntarioBiologics and BiosimilarsEtanerceptEnbrel®Yes - EAPYes - EAP
OntarioBiologics and BiosimilarsEtanerceptErelzi™Yes – L/U Yes – L/U
OntarioBiologics and BiosimilarsEtanerceptRymtiYes - L/UYes - L/U
OntarioBiologics and BiosimilarsGolimumabSimponi®N/AYes - EAP
OntarioBiologics and BiosimilarsGuselkumabTremfya®Yes - L/UYes - EAP
OntarioPrescription Topical TreatmentsHalobetasol propionate and tazaroteneDUOBRII®YesN/A
OntarioBiologics and BiosimilarsInfliximabAvsola®Yes – L/UYes – L/U
OntarioBiologics and BiosimilarsInfliximabInflectra®Yes – L/UYes – L/U
OntarioBiologics and BiosimilarsInfliximabOmvyence™NoNo
Prince Edward IslandBiologics and BiosimilarsAbataceptOrencia®NoNo
Prince Edward IslandSystemic DrugsAcitretinSoriatane®YesN/A
Prince Edward IslandBiologics and BiosimilarsAdalimumabHumira®Yes - S/AYes - S/A
Prince Edward IslandBiologics and BiosimilarsAdalimumabHadlima®Yes – S/AYes – S/A
Prince Edward IslandBiologics and BiosimilarsAdalimumabHyrimoz®Yes – S/AYes – S/A
Prince Edward IslandBiologics and BiosimilarsAdalimumabIdacio®Yes – S/AYes – S/A
Prince Edward IslandBiologics and BiosimilarsAdalimumabAmgevita®Yes - S/AYes - S/A
Prince Edward IslandBiologics and BiosimilarsAdalimumabHulio®Yes – S/AYes – S/A
Prince Edward IslandBiologics and BiosimilarsAdalimumabAbriladaYes – S/AYes – S/A
Prince Edward IslandBiologics and BiosimilarsAdalimumabSimlandiYes – S/AYes – S/A
Prince Edward IslandBiologics and BiosimilarsAdalimumabYuflymaYes – S/AYes – S/A
Prince Edward IslandSystemic DrugsApremilastOtezla®NoNo
Prince Edward IslandBiologics and BiosimilarsBimekizumabBimzelxYes – S/ANo
Prince Edward IslandBiologics and BiosimilarsBrodalumabSiliq™Yes – S/AN/A
Prince Edward IslandSystemic DrugsCelecoxibN/AYes
Prince Edward IslandBiologics and BiosimilarsCertolizumab pegolCimzia®NoYes – S/A
Prince Edward IslandPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_GelYesN/A
Prince Edward IslandPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_OintmentYesN/A
Prince Edward IslandPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsEnstilar™_FoamYesN/A
Prince Edward IslandSystemic DrugsCyclosporineYesN/A
Prince Edward IslandBiologics and BiosimilarsEtanerceptEnbrel®Yes – S/AYes – S/A
Prince Edward IslandBiologics and BiosimilarsEtanerceptErelzi™Yes – S/AYes – S/A
Prince Edward IslandBiologics and BiosimilarsEtanerceptBrenzys®Yes – S/AYes – S/A
Prince Edward IslandBiologics and BiosimilarsGolimumabSimponi®NoYes – S/A
Prince Edward IslandBiologics and BiosimilarsGuselkumabTremfya®Yes – S/AYes – S/A
Prince Edward IslandPrescription Topical TreatmentsHalobetasol propionate and tazaroteneDUOBRII®NoN/A
Prince Edward IslandBiologics and BiosimilarsInfliximabRemicade®Yes – S/AYes – S/A
Prince Edward IslandBiologics and BiosimilarsInfliximabAvsola®Yes – S/AYes – S/A
Prince Edward IslandBiologics and BiosimilarsInfliximabInflectra®Yes – S/AYes – S/A
QuebecBiologics and BiosimilarsAbataceptOrencia®NoNo
QuebecSystemic DrugsAcitretinSoriatane®YesN/A
QuebecBiologics and BiosimilarsAdalimumabHumira®Yes - S/A. If treatment began before August 19, 2020.Yes - S/A. If treatment began before August 19, 2020.
QuebecBiologics and BiosimilarsAdalimumabHadlima®Yes - S/AYes - S/A
QuebecBiologics and BiosimilarsAdalimumabHyrimoz®Yes – S/AYes – S/A
QuebecBiologics and BiosimilarsAdalimumabIdacio®Yes – S/AYes – S/A
QuebecBiologics and BiosimilarsAdalimumabAmgevita®Yes – S/AYes – S/A
QuebecBiologics and BiosimilarsAdalimumabHulio®Yes – S/AYes – S/A
QuebecBiologics and BiosimilarsAdalimumabAbriladaYes – S/AYes – S/A
QuebecBiologics and BiosimilarsAdalimumabSimlandiYes – S/AYes – S/A
QuebecBiologics and BiosimilarsAdalimumabYuflymaYes – S/AYes – S/A
QuebecSystemic DrugsApremilastOtezla®Yes – S/ANo
QuebecBiologics and BiosimilarsBimekizumabBimzelxYes – S/ANo
QuebecBiologics and BiosimilarsBrodalumabSiliq™Yes – S/AN/A
QuebecSystemic DrugsCelecoxibCelebrexN/AYes
QuebecBiologics and BiosimilarsCertolizumab pegolCimzia®NoYes – S/A
QuebecPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_GelYes – S/AN/A
QuebecPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_OintmentYes – S/AN/A
QuebecPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsEnstilar™_FoamYes – S/AN/A
QuebecSystemic DrugsCyclosporineYesN/A
QuebecBiologics and BiosimilarsEtanerceptEnbrel®Yes – S/A. If treatment began before August 19, 2020 Yes – S/A. If treatment began before August 19, 2020 
QuebecBiologics and BiosimilarsEtanerceptErelzi™Yes – S/AYes – S/A 
QuebecBiologics and BiosimilarsEtanerceptBrenzys®Yes – S/AYes – S/A
QuebecBiologics and BiosimilarsEtanerceptRymtiYes – S/AYes – S/A
QuebecBiologics and BiosimilarsGolimumabSimponi®N/AYes – S/A
QuebecBiologics and BiosimilarsGuselkumabTremfya®Yes - S/ANo
QuebecPrescription Topical TreatmentsHalobetasol propionate and tazaroteneDUOBRII®Yes - S/AN/A
QuebecBiologics and BiosimilarsInfliximabRemicade®Yes – S/A. If treatment began before August 19, 2020 Yes – S/A. If treatment began before August 19, 2020 
QuebecBiologics and BiosimilarsInfliximabAvsola®Yes - S/AYes - S/A
QuebecBiologics and BiosimilarsInfliximabInflectra®Yes - S/AYes - S/A
SaskatchewanBiologics and BiosimilarsAbataceptOrencia®NoNo
SaskatchewanSystemic DrugsAcitretinSoriatane®Yes – EDSN/A
SaskatchewanBiologics and BiosimilarsAdalimumabHumira®NoNo
SaskatchewanBiologics and BiosimilarsAdalimumabHadlima®Yes – EDSYes – EDS
SaskatchewanBiologics and BiosimilarsAdalimumabHyrimoz®Yes – EDSYes – EDS
SaskatchewanBiologics and BiosimilarsAdalimumabIdacio®Yes – EDSYes – EDS
SaskatchewanBiologics and BiosimilarsAdalimumabAmgevita®Yes – EDSYes – EDS
SaskatchewanBiologics and BiosimilarsAdalimumabHulio®Yes – EDSYes – EDS
SaskatchewanBiologics and BiosimilarsAdalimumabAbriladaYes – EDSYes – EDS
SaskatchewanBiologics and BiosimilarsAdalimumabSimlandiYes – EDSYes – EDS
SaskatchewanBiologics and BiosimilarsAdalimumabYuflymaYes – EDSYes – EDS
SaskatchewanSystemic DrugsApremilastOtezla®NoNo
SaskatchewanBiologics and BiosimilarsBimekizumabBimzelxYes - EDSNo
SaskatchewanBiologics and BiosimilarsBrodalumabSiliq™Yes – EDSNo
SaskatchewanSystemic DrugsCelecoxibCelebrexYesYes
SaskatchewanBiologics and BiosimilarsCertolizumab pegolCimzia®NoYes – EDS
SaskatchewanPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_GelYesN/A
SaskatchewanPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_OintmentYesN/A
SaskatchewanPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsEnstilar™_FoamYesN/A
SaskatchewanSystemic DrugsCyclosporineYes – EDSN/A
SaskatchewanBiologics and BiosimilarsEtanerceptEnbrel®NoNo
SaskatchewanBiologics and BiosimilarsEtanerceptErelzi™Yes – EDS Yes – EDS
SaskatchewanBiologics and BiosimilarsEtanerceptBrenzys®Yes – EDSYes – EDS
SaskatchewanBiologics and BiosimilarsGolimumabSimponi®NoYes – EDS
SaskatchewanBiologics and BiosimilarsGuselkumabTremfya®Yes - EDSYes - EDS
SaskatchewanPrescription Topical TreatmentsHalobetasol propionate and tazaroteneDUOBRII®YesN/A
SaskatchewanBiologics and BiosimilarsInfliximabRemicade®NoNo
SaskatchewanBiologics and BiosimilarsInfliximabAvsola®Yes – EDSYes – EDS
SaskatchewanBiologics and BiosimilarsInfliximabInflectra®Yes – EDSYes – EDS
YukonBiologics and BiosimilarsAbataceptOrencia®NoNo
YukonSystemic DrugsAcitretinSoriatane®Yes – EDSN/A
YukonBiologics and BiosimilarsAdalimumabHumira®Yes - EDSYes - EDS
YukonBiologics and BiosimilarsAdalimumabHadlima®Yes - EDSYes - EDS
YukonBiologics and BiosimilarsAdalimumabHyrimoz®Yes - EDSYes - EDS
YukonBiologics and BiosimilarsAdalimumabIdacio®Yes - EDSYes - EDS
YukonBiologics and BiosimilarsAdalimumabAmgevita®Yes - EDSYes - EDS
YukonBiologics and BiosimilarsAdalimumabHulio®Yes - EDSYes - EDS
YukonBiologics and BiosimilarsAdalimumabAbriladaYes - EDSYes - EDS
YukonBiologics and BiosimilarsAdalimumabSimlandiYes - EDSYes - EDS
YukonBiologics and BiosimilarsAdalimumabYuflymaYes - EDSYes - EDS
YukonSystemic DrugsApremilastOtezla®NoNo
YukonBiologics and BiosimilarsBimekizumabBimzelxNoNo
YukonBiologics and BiosimilarsBrodalumabSiliq™NoN/A
YukonSystemic DrugsCelecoxibN/AYes
YukonBiologics and BiosimilarsCertolizumab pegolCimzia®NoYes – EDS
YukonPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_GelYesN/A
YukonPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsDovobet®_OintmentYesN/A
YukonPrescription Topical TreatmentsCombination Vitamin D3 Analogues and CorticosteroidsEnstilar™_FoamYesN/A
YukonSystemic DrugsCyclosporineYesN/A
YukonBiologics and BiosimilarsEtanerceptEnbrel®Yes - EDS ; all new etanercept patients will be covered for Brenzys or ErelziYes – EDS; all new etanercept patients will be covered for Erelzi 
YukonBiologics and BiosimilarsEtanerceptErelzi™Yes - EDSYes – EDS
YukonBiologics and BiosimilarsEtanerceptBrenzys®Yes - EDSYes – EDS
YukonBiologics and BiosimilarsGolimumabSimponi®N/AYes – EDS
YukonBiologics and BiosimilarsGuselkumabTremfya®NoNo
YukonPrescription Topical TreatmentsHalobetasol propionate and tazaroteneDUOBRII®NoN/A
YukonBiologics and BiosimilarsInfliximabRemicade®Yes – EDS; all new infliximab patients will be covered for Inflectra brand only.Yes – EDS; all new infliximab patients will be covered for Inflectra brand only.
YukonBiologics and BiosimilarsInfliximabAvsola®NoNo
YukonBiologics and BiosimilarsInfliximabInflectra®Yes - EDSYes - EDS
AlbertaBiologics and BiosimilarsInfliximabOmvyence™NoNo
AlbertaBiologics and BiosimilarsInfliximabRemsima™NoNo
AlbertaBiologics and BiosimilarsInfliximabRenflexis®Yes – S/AYes – S/A
AlbertaBiologics and BiosimilarsIxekizumabTaltz®Yes – S/AYes – S/A
AlbertaSystemic DrugsLeflunomideArava®NoNo
AlbertaSystemic DrugsMethotrexateYesYes
AlbertaBiologics and BiosimilarsRisankizumabSkyrizi™Yes – S/AN/A
British ColumbiaBiologics and BiosimilarsInfliximabOmvyence™NoNo
British ColumbiaBiologics and BiosimilarsInfliximabRemsima™NoNo
British ColumbiaBiologics and BiosimilarsInfliximabRenflexis®Yes – S/AYes – S/A
British ColumbiaBiologics and BiosimilarsIxekizumabTaltz®Yes – S/AYes – S/A
British ColumbiaSystemic DrugsLeflunomideArava®YesYes
British ColumbiaSystemic DrugsMethotrexateYesYes
British ColumbiaBiologics and BiosimilarsRisankizumabSkyrizi™Yes – S/AN/A
ManitobaBiologics and BiosimilarsInfliximabOmvyence™NoNo
ManitobaBiologics and BiosimilarsInfliximabRemsima™NoNo
ManitobaBiologics and BiosimilarsInfliximabRenflexis®Yes – EDSYes – EDS
ManitobaBiologics and BiosimilarsIxekizumabTaltz®Yes – EDSYes – EDS
ManitobaBiologics and BiosimilarsIxekizumabSiliq™Yes – EDSN/A
ManitobaSystemic DrugsLeflunomideArava®NoNo
ManitobaBiologics and BiosimilarsRisankizumabSkyrizi™Yes – EDSN/A
New BrunswickBiologics and BiosimilarsInfliximabOmvyence™NoNo
New BrunswickBiologics and BiosimilarsInfliximabRemsima™NoNo
New BrunswickBiologics and BiosimilarsInfliximabRenflexis®Yes - S/AYes - S/A
New BrunswickBiologics and BiosimilarsIxekizumabTaltz®Yes – S/AYes – S/A
New BrunswickSystemic DrugsLeflunomideArava®N/AYes
New BrunswickSystemic DrugsMethotrexateYesYes
New BrunswickBiologics and BiosimilarsRisankizumabSkyrizi™Yes – S/AN/A
Newfoundland and LabradorBiologics and BiosimilarsInfliximabOmvyence™NoNo
Newfoundland and LabradorBiologics and BiosimilarsInfliximabRemsima™NoNo
Newfoundland and LabradorBiologics and BiosimilarsInfliximabRenflexis®Yes – S/AYes – S/A
Newfoundland and LabradorBiologics and BiosimilarsIxekizumabTaltz®Yes – S/AYes – S/A
Newfoundland and LabradorSystemic DrugsLeflunomideArava®N/AYes
Newfoundland and LabradorSystemic DrugsMethotrexateYesYes
Newfoundland and LabradorBiologics and BiosimilarsRisankizumabSkyrizi™Yes – S/AN/A
NIHBBiologics and BiosimilarsInfliximabOmvyence™NoNo
NIHBBiologics and BiosimilarsInfliximabRemsima™NoNo
NIHBBiologics and BiosimilarsInfliximabRenflexis®Yes - L/UYes - L/U
NIHBBiologics and BiosimilarsIxekizumabTaltz®Yes – L/UYes – L/U
NIHBSystemic DrugsLeflunomideArava®YesYes
NIHBSystemic DrugsMethotrexateYesYes
NIHBBiologics and BiosimilarsRisankizumabSkyrizi™Yes – L/UN/A
Northwest TerritoriesBiologics and BiosimilarsInfliximabOmvyence™NoNo
Northwest TerritoriesBiologics and BiosimilarsInfliximabRemsima™NoNo
Northwest TerritoriesBiologics and BiosimilarsInfliximabRenflexis®Yes - L/UYes - L/U
Northwest TerritoriesBiologics and BiosimilarsIxekizumabTaltz®Yes – L/UYes – L/U
Northwest TerritoriesSystemic DrugsLeflunomideArava®N/AYes
Northwest TerritoriesSystemic DrugsMethotrexateYesYes
Northwest TerritoriesBiologics and BiosimilarsRisankizumabSkyrizi™Yes – L/UN/A
Nova ScotiaBiologics and BiosimilarsInfliximabOmvyence™NoNo
Nova ScotiaBiologics and BiosimilarsInfliximabRemsima™NoNo
Nova ScotiaBiologics and BiosimilarsInfliximabRenflexis®Yes – EDSYes – EDS
Nova ScotiaBiologics and BiosimilarsIxekizumabTaltz®Yes – EDSYes – EDS
Nova ScotiaSystemic DrugsLeflunomideArava®N/AYes
Nova ScotiaSystemic DrugsMethotrexateYesYes
Nova ScotiaBiologics and BiosimilarsRisankizumabSkyrizi™Yes – EDSN/A
NunavutSystemic DrugsUpadacitinibRinvoq®N/ANo
NunavutBiologics and BiosimilarsEtanerceptRymtiNoYes - L/U
NunavutBiologics and BiosimilarsBrodalumabSiliq™Yes – L/UN/A
NunavutBiologics and BiosimilarsAdalimumabSimlandiYes - L/UYes - L/U
NunavutBiologics and BiosimilarsGolimumabSimponi®N/AYes – L/U
NunavutBiologics and BiosimilarsRisankizumabSkyrizi™Yes – L/UN/A
NunavutSystemic DrugsAcitretinSoriatane®YesN/A
OntarioBiologics and BiosimilarsInfliximabRemicade®Yes - EAPYes - EAP
OntarioBiologics and BiosimilarsInfliximabRemsima™NoNo
OntarioBiologics and BiosimilarsInfliximabRenflexis®Yes – L/UYes – L/U
OntarioBiologics and BiosimilarsIxekizumabTaltz®Yes – L/UYes - EAP
OntarioSystemic DrugsLeflunomideArava®YesYes
OntarioSystemic DrugsMethotrexateYesYes
OntarioBiologics and BiosimilarsRisankizumabSkyrizi™Yes – L/UN/A
Prince Edward IslandBiologics and BiosimilarsInfliximabOmvyence™NoNo
Prince Edward IslandBiologics and BiosimilarsInfliximabRemsima™NoNo
Prince Edward IslandBiologics and BiosimilarsInfliximabRenflexis®Yes – S/AYes – S/A
Prince Edward IslandBiologics and BiosimilarsIxekizumabTaltz®Yes – S/AYes – S/A
Prince Edward IslandSystemic DrugsLeflunomideArava®N/AYes
Prince Edward IslandSystemic DrugsMethotrexateYesYes
Prince Edward IslandBiologics and BiosimilarsRisankizumabSkyrizi™Yes – S/A N/A
QuebecBiologics and BiosimilarsInfliximabOmvyence™NoNo
QuebecBiologics and BiosimilarsInfliximabRemsima™NoNo
QuebecBiologics and BiosimilarsInfliximabRenflexis®Yes - S/AYes - S/A
QuebecBiologics and BiosimilarsIxekizumabTaltz®Yes – S/AYes – S/A
QuebecSystemic DrugsLeflunomideArava®N/AYes
QuebecSystemic DrugsMethotrexateYesYes
QuebecBiologics and BiosimilarsRisankizumabSkyrizi™Yes – S/AN/A
SaskatchewanBiologics and BiosimilarsInfliximabOmvyence™NoNo
SaskatchewanBiologics and BiosimilarsInfliximabRemsima™NoNo
SaskatchewanBiologics and BiosimilarsInfliximabRenflexis®Yes – EDSYes – EDS
SaskatchewanBiologics and BiosimilarsIxekizumabTaltz®Yes – EDSYes – EDS
SaskatchewanSystemic DrugsLeflunomideArava®NoYes – EDS
SaskatchewanSystemic DrugsMethotrexateYesYes
SaskatchewanBiologics and BiosimilarsRisankizumabSkyrizi™Yes – EDSN/A
YukonBiologics and BiosimilarsInfliximabOmvyence™NoNo
YukonBiologics and BiosimilarsInfliximabRemsima™NoNo
YukonBiologics and BiosimilarsInfliximabRenflexis®Yes - EDSYes - EDS
YukonBiologics and BiosimilarsIxekizumabTaltz®Yes - EDSYes - EDS
YukonSystemic DrugsLeflunomideArava®NoNo
YukonSystemic DrugsMethotrexateYesYes
YukonBiologics and BiosimilarsRisankizumabSkyrizi™Yes – EDSN/A
AlbertaBiologics and BiosimilarsSecukinumabCosentyx®Yes – S/AYes – S/A
AlbertaSystemic DrugsSulfasalazineYesYes
AlbertaBiologics and BiosimilarsTildrakizumabIlumya™Yes - SAN/A
AlbertaSystemic DrugsTofacitinibXeljanz®N/ANo
AlbertaPrescription Topical TreatmentsTopical RetinoidsTazaroteneYesN/A
AlbertaSystemic DrugsUpadacitinibRinvoq®N/AYes – S/A
AlbertaBiologics and BiosimilarsUstekinumabStelara®Yes – S/ANo
AlbertaBiologics and BiosimilarsUstekinumabWezlanaYes – S/ANo
AlbertaBiologics and BiosimilarsUstekinumabJamtekiYes – S/ANo
AlbertaPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcipotriol - Dovonex®YesN/A
AlbertaPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcitriol - Silkis®NoN/A
British ColumbiaBiologics and BiosimilarsSecukinumabCosentyx®Yes – S/AYes – S/A
British ColumbiaSystemic DrugsSulfasalazineSalazopyrinYesYes
British ColumbiaBiologics and BiosimilarsTildrakizumabIlumya™NoN/A
British ColumbiaSystemic DrugsTofacitinibXeljanz®N/ANo
British ColumbiaPrescription Topical TreatmentsTopical RetinoidsTazaroteneYesN/A
British ColumbiaSystemic DrugsUpadacitinibRinvoq®N/ANo
British ColumbiaBiologics and BiosimilarsUstekinumabStelara®Yes – S/A until Dec 3 2024No
British ColumbiaBiologics and BiosimilarsUstekinumabJamtekiYes - S/AYes - S/A
British ColumbiaPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcipotriol - Dovonex®YesN/A
British ColumbiaPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcitriol - Silkis®NoN/A
ManitobaBiologics and BiosimilarsSecukinumabCosentyx®Yes – EDSYes – EDS
ManitobaSystemic DrugsSulfasalazinepms-Sulfasalazine, SalazopyrinYesYes
ManitobaBiologics and BiosimilarsTildrakizumabIlumya™Yes - EDSN/A
ManitobaSystemic DrugsTofacitinibXeljanz®N/ANo
ManitobaPrescription Topical TreatmentsTopical RetinoidsTazaroteneNoN/A
ManitobaSystemic DrugsUpadacitinibRinvoq®N/AYes - EDS
ManitobaBiologics and BiosimilarsUstekinumabStelara®Yes – EDSNo
ManitobaPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcipotriol - Dovonex®YesN/A
ManitobaPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcitriol - Silkis®NoN/A
New BrunswickBiologics and BiosimilarsSecukinumabCosentyx®Yes – S/AYes – S/A
New BrunswickSystemic DrugsSulfasalazineSalazopyrinN/AYes
New BrunswickBiologics and BiosimilarsTildrakizumabIlumya™Yes - SAN/A
New BrunswickSystemic DrugsTofacitinibXeljanz®N/ANo
New BrunswickPrescription Topical TreatmentsTopical RetinoidsTazaroteneYes – S/AN/A
New BrunswickSystemic DrugsUpadacitinibRinvoq®N/AYes – S/A
New BrunswickBiologics and BiosimilarsUstekinumabStelara®NoNo
New BrunswickBiologics and BiosimilarsUstekinumabJamtekiYes - S/AYes - S/A
New BrunswickBiologics and BiosimilarsUstekinumabWezlanaYes - S/AYes - S/A
New BrunswickPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcipotriol - Dovonex®YesN/A
New BrunswickPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcitriol - Silkis®YesN/A
Newfoundland and LabradorBiologics and BiosimilarsSecukinumabCosentyx®Yes – S/AYes – S/A
Newfoundland and LabradorSystemic DrugsSulfasalazineN/AYes
Newfoundland and LabradorBiologics and BiosimilarsTildrakizumabIlumya™Yes – S/AN/A
Newfoundland and LabradorSystemic DrugsTofacitinibXeljanz®N/ANo
Newfoundland and LabradorPrescription Topical TreatmentsTopical RetinoidsTazaroteneNoN/A
Newfoundland and LabradorSystemic DrugsUpadacitinibRinvoq®N/AYes – S/A 
Newfoundland and LabradorBiologics and BiosimilarsUstekinumabStelara®Yes – S/ANo
Newfoundland and LabradorBiologics and BiosimilarsUstekinumabJamtekiYes – S/AYes – S/A
Newfoundland and LabradorBiologics and BiosimilarsUstekinumabWezlanaYes – S/AYes – S/A
Newfoundland and LabradorPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcipotriol - Dovonex®YesN/A
Newfoundland and LabradorPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcitriol - Silkis®NoN/A
NIHBBiologics and BiosimilarsSecukinumabCosentyx®Yes – L/UYes – L/U
NIHBSystemic DrugsSulfasalazineYesYes
NIHBBiologics and BiosimilarsTildrakizumabIlumya™Yes – L/UN/A
NIHBSystemic DrugsTofacitinibXeljanz®N/ANo
NIHBPrescription Topical TreatmentsTopical RetinoidsTazaroteneYesN/A
NIHBSystemic DrugsUpadacitinibRinvoq®N/AYes- L/U
NIHBBiologics and BiosimilarsUstekinumabStelara®Yes – L/UNo
NIHBBiologics and BiosimilarsUstekinumabWezlanaYes - L/UYes - L/U
NIHBPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcipotriol - Dovonex®YesN/A
NIHBPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcitriol - Silkis®NoN/A
Northwest TerritoriesBiologics and BiosimilarsSecukinumabCosentyx®Yes – L/UYes – L/U
Northwest TerritoriesSystemic DrugsSulfasalazineN/AYes
Northwest TerritoriesBiologics and BiosimilarsTildrakizumabIlumya™NoN/A
Northwest TerritoriesSystemic DrugsTofacitinibXeljanz®NoNo
Northwest TerritoriesPrescription Topical TreatmentsTopical RetinoidsTazaroteneYesN/A
Northwest TerritoriesSystemic DrugsUpadacitinibRinvoq®N/ANo
Northwest TerritoriesBiologics and BiosimilarsUstekinumabStelara®Yes – L/UNo
Northwest TerritoriesBiologics and BiosimilarsUstekinumabWezlanaYes – L/UYes – L/U
Northwest TerritoriesPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcipotriol - Dovonex®YesN/A
Northwest TerritoriesPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcitriol - Silkis®NoN/A
Nova ScotiaBiologics and BiosimilarsSecukinumabCosentyx®Yes – EDSYes - EDS
Nova ScotiaSystemic DrugsSulfasalazineN/AYes
Nova ScotiaBiologics and BiosimilarsTildrakizumabIlumya™Yes – EDSN/A
Nova ScotiaSystemic DrugsTofacitinibXeljanz®N/ANo
Nova ScotiaPrescription Topical TreatmentsTopical RetinoidsTazaroteneYes – EDSN/A
Nova ScotiaSystemic DrugsUpadacitinibRinvoq®N/AYes – EDS
Nova ScotiaBiologics and BiosimilarsUstekinumabStelara®Yes - EDSNo
Nova ScotiaBiologics and BiosimilarsUstekinumabJamtekiYes - EDSYes - EDS
Nova ScotiaBiologics and BiosimilarsUstekinumabWezlanaYes - EDSYes - EDS
Nova ScotiaPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcipotriol - Dovonex®Yes - EDSN/A
Nova ScotiaPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcitriol - Silkis®YesN/A
NunavutBiologics and BiosimilarsUstekinumabStelara®Yes – L/UNo
NunavutBiologics and BiosimilarsIxekizumabTaltz®Yes – L/UYes – L/U
NunavutPrescription Topical TreatmentsTopical RetinoidsTazaroteneYesN/A
NunavutBiologics and BiosimilarsGuselkumabTremfya®Yes - L/UYes - L/U
NunavutBiologics and BiosimilarsUstekinumabWezlanaYes – L/UYes – L/U
NunavutSystemic DrugsTofacitinibXeljanz®NoNo
NunavutBiologics and BiosimilarsAdalimumabYuflymaYes - L/UYes - L/U
NunavutSystemic DrugsCyclosporineYesYes
NunavutSystemic DrugsMethotrexateYesYes
NunavutSystemic DrugsSulfasalazineN/AYes
OntarioBiologics and BiosimilarsSecukinumabCosentyx®Yes – L/UYes - EAP
OntarioSystemic DrugsSulfasalazineN/AYes
OntarioBiologics and BiosimilarsTildrakizumabIlumya™Yes - L/UN/A
OntarioSystemic DrugsTofacitinibXeljanz®N/ANo
OntarioPrescription Topical TreatmentsTopical RetinoidsTazaroteneNoN/A
OntarioSystemic DrugsUpadacitinibRinvoq®N/ANo
OntarioBiologics and BiosimilarsUstekinumabStelara®Yes – L/UNo
OntarioBiologics and BiosimilarsUstekinumabJamtekiYes - L/UYes - L/U
OntarioBiologics and BiosimilarsUstekinumabWezlanaYes - L/UYes - L/U
OntarioPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcipotriol - Dovonex®Yes – L/UN/A
OntarioPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcitriol - Silkis®Yes – L/UN/A
Prince Edward IslandBiologics and BiosimilarsSecukinumabCosentyx®Yes – S/AYes – S/A
Prince Edward IslandSystemic DrugsSulfasalazineN/AYes
Prince Edward IslandBiologics and BiosimilarsTildrakizumabIlumya™Yes – S/AN/A
Prince Edward IslandSystemic DrugsTofacitinibXeljanz®NoNo
Prince Edward IslandPrescription Topical TreatmentsTopical RetinoidsTazaroteneNoN/A
Prince Edward IslandSystemic DrugsUpadacitinibRinvoq®N/AYes – S/A
Prince Edward IslandBiologics and BiosimilarsUstekinumabStelara®Yes – S/ANo
Prince Edward IslandPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcipotriol - Dovonex®YesN/A
Prince Edward IslandPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcitriol - Silkis®NoN/A
QuebecBiologics and BiosimilarsSecukinumabCosentyx®Yes – S/AYes – S/A
QuebecSystemic DrugsSulfasalazineN/AYes
QuebecBiologics and BiosimilarsTildrakizumabIlumya™NoN/A
QuebecSystemic DrugsTofacitinibXeljanz®N/ANo
QuebecPrescription Topical TreatmentsTopical RetinoidsTazaroteneNoN/A
QuebecSystemic DrugsUpadacitinibRinvoq®N/AYes – S/A 
QuebecBiologics and BiosimilarsUstekinumabStelara®Yes – S/AYes – S/A
QuebecBiologics and BiosimilarsUstekinumabJamtekiYes – S/AYes – S/A
QuebecBiologics and BiosimilarsUstekinumabWezlanaYes – S/AYes – S/A
QuebecPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcipotriol - Dovonex®YesN/A
QuebecPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcitriol - Silkis®YesN/A
SaskatchewanBiologics and BiosimilarsSecukinumabCosentyx®Yes – EDSYes – EDS
SaskatchewanSystemic DrugsSulfasalazineN/AYes
SaskatchewanBiologics and BiosimilarsTildrakizumabIlumya™Yes - EDSN/A
SaskatchewanSystemic DrugsTofacitinibXeljanz®N/ANo
SaskatchewanPrescription Topical TreatmentsTopical RetinoidsTazaroteneYesN/A
SaskatchewanSystemic DrugsUpadacitinibRinvoq®N/AYes – EDS
SaskatchewanBiologics and BiosimilarsUstekinumabStelara®Yes – EDSYes – EDS
SaskatchewanPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcipotriol - Dovonex®YesN/A
SaskatchewanPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcitriol - Silkis®NoN/A
YukonBiologics and BiosimilarsSecukinumabCosentyx®Yes – EDSYes – EDS
YukonSystemic DrugsSulfasalazineN/AYes
YukonBiologics and BiosimilarsTildrakizumabIlumya™NoN/A
YukonSystemic DrugsTofacitinibXeljanz®NoNo
YukonPrescription Topical TreatmentsTopical RetinoidsTazaroteneYesN/A
YukonSystemic DrugsUpadacitinibRinvoq®N/ANo
YukonBiologics and BiosimilarsUstekinumabStelara®Yes – EDSNo
YukonPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcipotriol - Dovonex®YesN/A
YukonPrescription Topical TreatmentsVitamin_D3_Analogues(Dovonex® Silkis®)Calcitriol - Silkis®YesN/A

More information is available on S/A (special access), L/U (limited use) and Exceptional Drug Status (EDS) at Special Access / Limited Use Designation Drugs.

NIHB stands for non-insured health benefits.

This site is updated regularly; however this information is subject to change. Access may also vary depending on the specific plan. For the most up-to-date information regarding your specific province / territory click here.

Last updated May 31, 2024.

This site is registered on wpml.org as a development site. Switch to a production site key to remove this banner.